Uzi Doorman, more commonly referred to as Uzi, is the main protagonist of Murder Drones. Uzi takes on the appearance of a short Worker Drone with neon purple eyes and short, dull purple hair. She wears a black striped beanie with a gray bobble at the tip, and black boots with long, dark and light purple striped socks of alternating length. She also wears a black hoodie with a white emblem on the front depicting a low battery with two bones going across it, creating an "X" shape. The bottom of the hoodie has two white stripes wrapping around it, and the left sleeve has a white Secchi disk symbol on it. The hoodie also has black fur around the bottom and the collar. She also has a black choker around her neck with a skull and the number "002" on it. Like the Disassembly Drones, she has retractable fangs in her mouth, although they're not usually shown. Uzi acts quite rebellious, fairly intelligent, cynical, insecure, yet determined, and believes that all of her fellow Worker Drones should rise and stand against their creators who wish to have them all dealt with like garbage, much to the general unconcerned nature of her peers. Serial Designation N, or simply known as N, is the deuteragonist of Murder Drones. N establishes the features of a male Disassembly Drone, with flared, boot-like legs instead of his female counterparts' cone-shaped legs. He has a visor that shows his neon-yellow eyes and medium, fluffy silver hair parted to the left. Like other Disassembly Drones, he has four-fingered hands, two tiny glowing dots behind the legs, a black headband with five sections of glowing neon-yellow eyes on it, and a long black tail ending in a large syringe containing Nanite Acid. He wears a short-sleeved black winter coat with a golden fur collar and a black belt, along with a black pilot hat with a white skull insignia. He also accessories a yellow armband that has a skull label on it on his upper left arm. As shown from a few shots, he also has small fangs. The bottom of his feet and his wrists end in yellow and black hazard stripes. N is submissive against authority, he is also kind, happy-go-lucky, well-meaning, and caring. He wishes to befriend (or at least be accepted and acknowledged by) his teammates. Serial Designation V, or simply known as V, is the tritagonist of Murder Drones. V has the features of a typical female Disassembly Drone, with wide hips and shins tapered to a point. She has neon-yellow eyes and a silver bob-cut hairstyle. She also possesses sharp, jagged teeth. As with the other Disassembly Drones, she has a black headband with five sections of eyes and a long black tail ending with a large syringe containing Nanite Acid. She wears a dark gray, short-sleeved crop coat with a golden fur collar and cuffs. Her legs are painted black up to her thighs, resembling white shorts or thigh-high socks, with yellow and black stripes at the end of her legs. She also accessories a yellow armband with a skull label on it, along with some text, which contains her P/N (CYN-MYKX) and S/N (V-X00100000). V, on the surface, appears as a sociopathic, mean, violent, impulsive, and sadistic mass murderer, who has no qualms or regrets for murdering Worker Drones. However, underneath this exterior lies a traumatized and complex individual who seeks to keep her friends safe at any cost. Serial Designation J, or simply known as J, is one of the two secondary antagonists in Murder Drones. Serial Designation J has the distinctive features of a female Disassembly Drone, with wide hips and shins tapered to a point. She has silver hair styled in high-sleek twin silver-colored ponytails, tied with black ribbons. Like other Disassembly Drones, she has neon yellow eyes and a black headband adorned with five additional eyes that contain Nanite Acid and match the color displayed on her visor, as well as a long, thin black tail ending in a large syringe also filled with Nanite Acid. She also possesses jagged teeth. Her attire consists of a short-sleeved black shirt with side pockets under it, a black leather belt giving it as a skirt, a dark yellow shirt beneath her blazer, and a tie, giving her the appearance of professionalism, especially in comparison to the other two members of her squadron. As for her legs, it appears as though she is wearing knee-high stockings with visible suspenders, but this is in actuality just the coloration of her chassis. On her left arm, she wears a yellow armband marked with a skull emblem, signifying her role and identity as a Disassembly Drone. When in combat mode, she reveals jagged teeth, and her visor displays an "X" shape, signaling her aggressive intent. Her appearance is further heightened by large metal wings with a yellow and black color pattern and possesses 16 feather blades, with the middle of these wings being two yellow glowing circles. She is demonstrated to have interchangeable hands that she can switch out for other tools and weapons that can aid her in her missions, one of which are three-sharp claws, which enables her to tear through targets with ease. J is best described as a "lethal workaholic," as she is incredibly dedicated to her job - even using corporate jargon like "synergistic liability" and "fourth-quarter profits" in place of insults or vulgarism.