Synopsis: Rentaro Aijo has confessed to, and been rejected by, 100 girls in his lifetime. On the last day of middle school, he visits a shrine and prays that he get a girlfriend during his time at high school. Suddenly, the God of Love appears and tells Rentaro that the reason for his non-existent love life is because everyone is only supposed to have one soulmate in their life. Due to a clerical error on the God of Love's part, Rentaro is destined to have 100 which is to begin when he enters high school. Sure enough, on the first day of high school, Rentaro meets the nymphomaniacal Hakari Hanazono and tsundere Karane Inda, the first two soulmates. They experience love at first sight, but Rentaro cannot decide between the two. That evening, he revisits the God of Love and is informed that if he does not return the feelings of any of his 100 soulmates, they will die in an accident. Not wanting such a fate to befall the girls, Rentaro decides to date all of them simultaneously, beginning with Hakari and Karane with their blessing. As the story continues, more girls are introduced and become Rentaro's girlfriends, establishing a polyamorous relationship called the "Rentaro Family". The story revolves around Rentaro meeting new girlfriends and the interactions between the Rentaro Family members. Characters: Rentarou Aijou - The fiercely dedicated, superhumanly romantic protagonist. He is the ultimate gentleman; possessive of superhuman determination, an infinite capacity for love, and an absolute willingness to sacrifice his own body or sanity to keep every single girlfriend happy and safe. Hakari Hanazono: The deeply affectionate, wealthy, and flirtatious co-first girlfriend. She is a clever, intensely romantic, and openly perverted "deredere" who constantly plots sensual, physical ways to get closer to Rentarou. Karane Inda - The fiercely powerful, tsundere co-first girlfriend who uses aggression to mask her immense love. She is a textbook, extreme tsundere with immense physical strength who fiercely covers up her deeply caring, fragile emotional side with anger and violent denials. Shizuka Yoshimoto - The tiny, hyper-shy library assistant who communicates via a phone text-to-speech app. She is extremely gentle, timid, and fragile; she has a massive inferiority complex about speaking and expresses her profound affection through literary quotes. Nano Eiai - The robotic, ultra-efficient logic-lover who optimized her life until she fell for Rentarou. She is an ultra-logical, robotic intellect who initially rejected emotions as "inefficient," but has since learned to deeply cherish romance through a lens of extreme calculation. Kusuri Yakuzen - The chaotic 18-year-old chemistry genius stuck in a child’s body due to her own experimental drugs. She is an chaotic, hyperactive mad scientist who speaks with a goofy sentence filler ("-yep yep") and views the world as an endless playground for crazy chemical experiments. Hahari Hanazono: Hakari's stunningly wealthy, overly doting mother and high school chairwoman. She is a fiercely protective mother who transformed into an unabashedly baby-obsessed, boundary-crossing pervert who aggressively showers Rentarou and the younger family members with overwhelming affection. Kurumi Haraga - The short-tempered girl with an insanely high metabolism who gets grumpy whenever she is hungry. She is the girl with a classic "hangry" personality; she is incredibly prickly, defensive, and sharp-tongued, but becomes a sweet, easily flustered softie the moment her stomach is full. Mei Meido - Hahari's hyper-competent personal maid who possesses dog-like loyalty and keeping her eyes perpetually closed. She is an absolutely selfless, hyper-loyal servant who lacks self-preservation instincts; she views her own life as worthless compared to the happiness of Hahari and Rentarou. Iku Sutou - The relentless kendo/baseball player who channels her massive masochistic streaks into extreme athletic training. She is an relentless tomboy and extreme closet masochist who interprets exhausting hard work, sports injuries, and harsh discipline as pure, euphoric pleasure. Mimimi Utsukushisugi - The dramatic upperclassman entirely obsessed with narcissism, personal beauty, and flashiness. She is an intensely theatrical, gloriously narcissistic upperclassman who firmly believes beauty requires hard work, yet she is surprisingly humble, generous, and supportive of others. Meme Kakure - The deeply anxious girl who hides her face behind massive bangs and uses ninja-like misdirection to vanish. She is an incredibly shy, anxiety-ridden girl who experiences immediate panic when noticed; she uses master-level ninja tricks to hide or substitute her body with plushies. Chiyo Lin - Originally introduced as Rentarou's cousin and later become his 12th girlfriend. She acts as a strict, rule-abiding disciplinary figure who finds public displays of affection proper but embarrassing, she grows deeply attached to Rentarou and her fellow girlfriends. When her glasses are removed, her personality flips entirely. She loses her strict demeanor, becomes incredibly anxious, and cries uncontrollably. Nadeshiko Yamato (Naddy) - A Japanese teacher who rejects tradition, wears western clothing, and speaks in a fake, heavily stylized American slang. She has an deeply rebellious free spirit who vehemently rejects her strict traditional upbringing to live a loud, chaotic, and heavily stereotyped "American Dream". Yamame Yasashiki - A giant, incredibly tall gardening club member who loves nature so much she refuses to hurt even weeds or bugs. She is a pacifist "gentle giant" with a boundless empathy for nature; she genuinely weeps over stepped-on weeds and refuses to let any living creature be harmed. Momiji Momi - A middle-school girl who treats tactile touch like an art form, possessing legendary massage skills. She is an unreadable, soft-spoken girl with a laser-focused obsession with tactile touch; she handles massages like a fine art and tactfully seeks out soft things to squeeze. Yaku Yakuzen - Kusuri's 89-year-old grandmother who looks like a child due to the same body-altering drug. She is a wise, deeply serene, and playfully teasing grandmother who looks at modern technology with utter confusion while retaining a sharp, mature emotional intelligence. Kishika Torotoro - The strict, honorable kendo captain who secretly hides a desperate, massive urge to be babied and pampered. She is a fiercely disciplined, severe kendo master who harbors a secret, crippling desire to revert to a helpless baby and be heavily pampered when away from the public eye. Aashii Kedarui (Ahko) - The ultra-laid-back, sweet gyaru who speaks in heavy valley-girl slang and radiates pure positive vibes. She is a blissfully relaxed, hyper-positive gyaru who speaks in slow valley-girl slang and acts as an emotional anchor, entirely incapable of holding a grudge. Uto Nakaji - The chuunibyou wanderer who dresses like a traveling bard and plays a recorder badly while speaking in vague paradoxes. She is a deeply eccentric chuunibyou who fancies herself a poetic, nomadic bard; she speaks entirely in intentionally confusing, deep-sounding paradoxes. Mai Meido - Mei's junior maid who desperately wants to be viewed as a perfect cool professional but is an incredibly clumsy tsundere. She is a clumsy, incredibly easily flustered try-hard who desperately wants to be a "cool, mature maid" but collapses into a blushing mess whenever teased. Momoha Bonnouji - The school's ethics counselor who ironically lives in a tent on campus, drinks heavily, and gambles away her money. She is a wildly contradictory school ethics teacher who is a hedonistic trainwreck in private—constantly drinking, gambling, and sleeping in a tent on campus. Rin Baio - A polite, wealthy violinist who harbors a secret, intense fixation on gory horror films and ultra-violent entertainment. She is a perfectly poised, highly refined classical violinist who secretly harbors an intense, bloodthirsty love for extreme violence, gore, and horror slasher tropes. Suu Hifumi - An eccentric girl who is entirely, exclusively attracted to physical mathematical numbers rather than human beings. She is an incredibly detached girl who lacks typical human empathy because she is romantically and physically infatuated with numbers (especially the number 3). Eira Kaho - A capoeira martial artist who can kick through anything except her absolute, crippling fear of abstract concepts like ghosts or bad luck. She is a fiercely confident, protective martial artist who will instantly kick physical threats but turns into a screaming, sobbing coward when facing abstract, un-kickable things like ghosts. Tama Nekonari - An ex-office worker who suffered a breakdown from burnout and now lives full-time pretending to be a domestic housecat. She is a deeply burnt-out, recovering workaholic who completely rejected human society to live a low-stress, pampered life pretending to be a literal household cat. Himeka Saiki (Kiki) - A famous prodigy pop-idol who intentionally does bizarre, abnormal things because she has a deep obsession with being "weird". She is a beautifully gifted pop star who suffers from a compulsive obsession with being weird; she actively hates doing things normally or efficiently. Matsuri Dei - A festival-loving spitfire girl who operates traditional food stalls and speaks in a rough, old-school downtown Tokyo accent. She is a fiercely proud, stubborn, and short-tempered festival stall worker who acts like an old-school Tokyo street merchant but hides a deeply lonely heart. Shiina Usami - A girl with a massive plush bunny addiction who suffers from severe separation anxiety and cannot stand being physically alone. She is a girl with catastrophic separation anxiety who experiences immediate physical and mental distress if she is not attached to or cuddling someone. Meru Zetsubouda - A gothic novelist who sees the entire world through a lens of existential despair and fairy tale tragedy. She is a deeply gloomy, melodramatic gothic novelist who interprets every daily occurrence as a tragic, beautiful curse destined for a grim fairy tale ending. Saki Tomogara - A tough delinquent girl with a secret soft spot for cute things and helping others. She is a fiercely protective, hot-headed "delinquent" who tries to maintain a terrifying, tough-guy persona but is easily defeated by anything cute. Nemu Nemui - A girl who is perpetually exhausted, sleeping through almost any event while remaining oddly active. She is a chronically exhausted girl who acts gloomy when awake due to low self-esteem, but transforms into a cheerful, incredibly active sleepwalker when she closes her eyes. Hasuha Hasu - A chaotic, fast-talking girl with distinct personality quirks. She is a hyper-fast talking, chaotic girl who rapidly shifts between intense emotional bursts and high-speed analytical chatter. Kimari Morikita - An energetic addition with her own specialized habits. She is a trendy, intensely rule-abiding gal whose obsession with social laws makes her treat rule-breaking like a forbidden, dangerous thrill. Eru Futate - A girl added to the expanding list of unique high school dynamic characters. She is a highly theatrical girl who views her interactions through a classic romantic drama lens, looking for cinematic "darling" moments. Chiyu Jiai - A girlfriend who contributes to the family's chaotic high school sub-clubs. She is a deeply affectionate, highly attentive girl who treats the family like a sanctuary, focusing entirely on providing comfort and care. Kogoe Mishiro - A uniquely timid girl who shares a class with Rentarou and the others. She is a profoundly timid and insecure girl who believes her natural "sanpaku" eyes look terrifying, causing her to live in constant fear of accidentally scaring people away. Rana Fushida - The latest soulmate to join Rentarou's ever-growing polyamorous circle. She is a highly organized, responsible class president who struggles with severe insecurity over her voluptuous body, fearing that people judge her as promiscuous when she is actually highly proper.